1-(2-Methoxyphenyl)piperazine → HCID 13729391, compound

HRID 1906437Notes

Reaction equation

HRID 1906437 reaction equation
[C:1]([C:4]1[O:5][C:6]2[CH:12]=[C:11]([O:13][CH2:14][CH:15]([OH:18])[CH2:16]Cl)[CH:10]=[CH:9][C:7]=2[CH:8]=1)(=[O:3])[CH3:2].[CH3:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[C:1]([C:4]1[O:5][C:6]2[CH:12]=[C:11]([O:13][CH2:14][CH:15]([OH:18])[CH2:16][N:30]3[CH2:29][CH2:28][N:27]([C:22]4[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=4[O:20][CH3:19])[CH2:32][CH2:31]3)[CH:10]=[CH:9][C:7]=2[CH:8]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 20211999HCID 20211999, compound

Product 1

HCID 13729391HCID 13729391, compound

Procedure

The procedures of Example 2b were repeated except that 1.3 g (0.005 mole) of 2-acetyl-6-(3-choro-2-hydroxypropoxy)benzofuran and 1.1 g (0.0055 mole) of 1-(2-methoxyphenyl)piperazine were employed as starting materials. The obtained concentrated residue was crystallized from ethyl acetate.

Workup

  1. customThe obtained concentrated residue was crystallized from ethyl acetate

Sources & evidence

ORD record
ord-e9e900a3d3ff4b58a53056f5de24687d
Source dataset
uspto-grants-1987_03
Patent number
US04652566

Reaction notes

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