1-(o-Tolyl)piperazine Hydrochloride → HCID 13729393, compound

HRID 1906443Notes

Reaction equation

HRID 1906443 reaction equation
[C:1]([C:4]1[O:5][C:6]2[CH:12]=[C:11]([O:13][CH2:14][CH:15]3[O:17][CH2:16]3)[CH:10]=[CH:9][C:7]=2[CH:8]=1)(=[O:3])[NH2:2].Cl.[CH3:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[C:1]([C:4]1[O:5][C:6]2[CH:12]=[C:11]([O:13][CH2:14][CH:15]([OH:17])[CH2:16][N:29]3[CH2:30][CH2:31][N:26]([C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=4[CH3:19])[CH2:27][CH2:28]3)[CH:10]=[CH:9][C:7]=2[CH:8]=1)(=[O:3])[NH2:2]

Participants

3

Reactant 2

HCID 122278951-(o-Tolyl)piperazine HydrochlorideHCID 13729404HCID 13729404, compound

Product 1

HCID 13729393HCID 13729393, compound

Procedure

The procedures of Example 10 were repeated except that 1.2 g (0.005 mole) of 2-carbamoyl-6-(2,3-epoxypropoxy)benzofuran and 1.1 g (0.0055 mole) of 1-(2-methylphenyl)piperazine hydrochloride were employed. The obtained residue was crystallized from ethyl acetate and ether.

Workup

  1. customThe obtained residue was crystallized from ethyl acetate and ether

Sources & evidence

ORD record
ord-fc8aa4738f0a4faca9ea63149c60bfe2
Source dataset
uspto-grants-1987_03
Patent number
US04652566

Reaction notes

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