1-(2-Methoxyphenyl)piperazine → HCID 13729389, compound

HRID 1906445Notes

Reaction equation

HRID 1906445 reaction equation
[O:1]1[CH2:17][CH:2]1[CH2:3][O:4][C:5]1[C:13]2[O:12][C:11]([CH:14]([OH:16])[CH3:15])=[CH:10][C:9]=2[CH:8]=[CH:7][CH:6]=1.[CH3:18][O:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[OH:16][CH:14]([C:11]1[O:12][C:13]2[C:5]([O:4][CH2:3][CH:2]([OH:1])[CH2:17][N:29]3[CH2:28][CH2:27][N:26]([C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=4[O:19][CH3:18])[CH2:31][CH2:30]3)=[CH:6][CH:7]=[CH:8][C:9]=2[CH:10]=1)[CH3:15]

Participants

3

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 20211997HCID 20211997, compound

Product 1

HCID 13729389HCID 13729389, compound

Procedure

The procedures of Example 1 were repeated except that 1.2 g (0.005 mole) of 7-(2,3-epoxypropoxy)-(1-hydroxyethyl)benzofuran and 1.1 g (0.0055 mole) of 1-(2-methoxyphenyl)piperazine were employed. The obtained concentrated residue was crystallized from ether acetate.

Workup

  1. customThe obtained concentrated residue was crystallized from ether acetate

Sources & evidence

ORD record
ord-a265e0d408214ec29a70511d39e9cc5d
Source dataset
uspto-grants-1987_03
Patent number
US04652566

Reaction notes

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