HuagongsheHuagongshe Chemistry Print Report · For research reference only
Keto-pantoyllactone → D-Pantolactone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Keto-pantoyllactone | HCID 39 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | D-Pantolactone | HCID 439368 | — |
Reaction Steps
The hydrogenation of 40.0 g of ketopantolactone, dissolved in 110 ml of toluene, with 100 ml of catalyst solution prepared according to Example 36 was carried out as described in Example 29. After a hydrogenation time of 2 hours the mixture was worked-up analogously to Example 2. pure (R)-pantolactone being obtained. [α]D20 =-47.9°. Optical purity 92.8%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04652657 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-4cff33d3388a400b92b9bf8a9ef5df1a |
| Source note | uspto-grants-1987_03 |