HCID 15058021, compound → HCID 15058025, compound

Participants

Reaction Steps

420 mg (1 mmol) of 3-[(3S,4S)-2-oxo-3-tritylamino-4-azetidinyl]-2-propynyl acetate are hydrogenated in the same manner with platinum oxide and the product is chromatographed over 70 g of silica gel with t-butyl methyl ether/n-hexane (1:1). After 125 ml, there are obtained 300 mg of (3S,4S)-4-propyl-3-tritylamino-2-azetidinone and, after 275 ml, there are obtained 87 mg of 3-[(3S,4S)-2-oxo-3-tritylamino-4-azetidinyl]-propyl acetate.

Provenance & Evidence