Cyclohexyl isocyanate → HCID 13763783, compound

Participants

Reaction Conditions

Reaction Steps

To a cooled solution (ice-water at 10° C.) of 2-adamantanone oxime (5.0 g, 0.03 mol) in 300 ml dichloromethane was added dropwise cyclohexyl isocyanate (3.77 g, 0.03 mol) in dichloromethane (25 ml). The resulting solution was stirred at 10° C. for 3-4 h, then the solvent was evaporated under reduced pressure to yield the title compound, tricyclo[3.3.1.13,7 ]decane-2-one O-[(cyclohexyl)aminocarbonyl]oxime. After repeated crystallization from ether-hexane, 6.2 g of the title compound were obtained as white crystals (m.p., 110°-112° C.).

Provenance & Evidence