Ammonia → HCID 178508284, compound

HRID 1906725Notes

Reaction equation

HRID 1906725 reaction equation
[NH3:1].Cl[C:3]1[NH:4][SH:5](=[O:21])([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:6]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:8]=1.O>C(O)C>[NH2:1][C:3]1[NH:4][SH:5](=[O:21])([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:6]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:8]=1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 962WaterHCID 178527218HCID 178527218, compound

Product 1

HCID 178508284HCID 178508284, compoundYield 93%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
100 °C

Procedure

To 75 ml of saturated a solution of ammonia in ethanol was added 3 g (0.01 mole) of 3-chloro-1,5-diphenyl-1H-1,2,4-thiadiazine-1-oxide and the mixture was heated in an autoclave at 100° C. for 3 hours. The mixture was cooled, poured into water and the product was filtered off, washed with water and dried to obtain 2.6 g (93%) of 3-amino-1,5-diphenyl-1H-1,2,4-thiadiazine-1-oxide melting at 169°-170° C.

Workup

  1. temperatureThe mixture was cooled
  2. filtrationthe product was filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-b7803fe04d4048b7acb8df8c0ba065b5
Source dataset
uspto-grants-1987_03
Patent number
US04654338

Reaction notes

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