HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzylamine → N-[(2-Chlorophenyl)methyl]-1-methyl-1H-imidazo[4,5-c]pyridin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzylamine | HCID 66648 | — |
| Reactant | 1-Methyl-4-(methylsulfanyl)-1H-imidazo[4,5-c]pyridine | HCID 20210762 | — |
| Product | N-[(2-Chlorophenyl)methyl]-1-methyl-1H-imidazo[4,5-c]pyridin-4-amine | HCID 13264442 | — |
Reaction Steps
A mixture of 17.9 of 1-methyl-4-methylthio-1H-imidazo(4,5-c)pyridine (m.p. 170°-175°) and 28 g of o-chlorobenzylamine is heated to 170°-180° for 20 hours. After cooling and customary working up, 4-o-chlorobenzylamino-1-methyl-1H-imidazo(4,5-c)pyridine of m.p. 173°-176° is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04654350 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-a5f9a170b2d34c46958d18a4e88a7ec8 |
| Source note | uspto-grants-1987_03 |