HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → Bamaluzole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2-Chlorobenzyl alcohol | HCID 28810 | — |
| Reactant | 4-chloro-1-methyl-1H-imidazo(4,5-c)pyridine | HCID 948792 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Bamaluzole | HCID 3086242 | — |
Reaction Steps
A mixture of 7.5 g of 4-chloro-1-methyl-1H-imidazo(4,5-c)pyridine, 7.1 g of 2-chlorobenzyl alcohol, 3.3 g of KOH and 100 ml of acetonitrile is refluxed for 7 hours. The solvent is removed and the residue is worked up in the customary manner (water/methylene chloride) to give 4-o-Chlorobenzyloxy-1-methyl-1H-imidazo(4,5-c)pyridine, m.p. 132°-135°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04654350 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-9c75251ce62041259494c3e9c8a4fb0a |
| Source note | uspto-grants-1987_03 |