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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1906844Generated: November 1, 2026

Dimethylformamide dimethyl acetal → N-[3-(3-Dimethylaminoacryloyl)phenyl]acetamide

https://huagongshe.com/reaction/1906844

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamide dimethyl acetalHCID 78373—
Reactant3'-AcetamidoacetophenoneHCID 346202—
ProductN-[3-(3-Dimethylaminoacryloyl)phenyl]acetamideHCID 53412415—

Reaction Steps

A 10.4 g portion of N-(3-acetylphenyl)acetamide was reacted with 25 ml of dimethylformamide dimethylacetal for 8 hours under argon giving N-[3-[3-(dimethylamino)-1-oxo-2-propenyl]phenyl]acetamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04654347
Source datasetuspto-grants-1987_03
ORD IDord-188d8a00dabe475eae528db4a6b97c01
Source noteuspto-grants-1987_03