Thionyl Chloride → HCID 13826416, compound

HRID 1906919Notes

Reaction equation

HRID 1906919 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[C:9]2[C:4](=[CH:5][C:6]([Cl:13])=[CH:7][CH:8]=2)[C:3]=1[CH2:14]O.S(Cl)([Cl:18])=O>>[Cl:18][CH2:14][C:3]1[C:4]2[C:9](=[CH:8][CH:7]=[C:6]([Cl:13])[CH:5]=2)[C:10]([Cl:12])=[CH:11][C:2]=1[Cl:1]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 13826415HCID 13826415, compound

Product 1

HCID 13826416HCID 13826416, compound

Procedure

(2,4,7-Trichloronaphthalen-1-yl)methanol (1.0 g, 3.8 mmoles) was added portionwise to thionyl chloride (10 ml) with cooling (ice bath). The reaction mixture was stirred at room temperature for 30 minutes and at reflux for 2 hours and then concentrated to dryness in vacuo. The oily residue was taken up in methylene chloride and the solution dried over MgSO4. The solution was filtered and concentrated in vacuo to give 1.0 g of the title compound.

Workup

  1. temperaturewith cooling (ice bath)
  2. temperatureat reflux for 2 hours
  3. concentrationconcentrated to dryness in vacuo
  4. dry with materialthe solution dried over MgSO4
  5. filtrationThe solution was filtered
  6. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-e98f61805c684a1b8fd945bb0224af58
Source dataset
uspto-grants-1987_03
Patent number
US04654363

Reaction notes

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