5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridine → 2-(4-morpholino-2-(1H-pyrrolo[2,3-b]pyridin-5-yl)thieno[2,3-d]pyrimidin-6-yl)propan-2-ol

HRID 190693Notes

Reaction equation

HRID 190693 reaction equation
[CH3:21][C:22]1([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27][B:28]([c:29]2[cH:30][c:31]3[c:32]([n:33][cH:34]2)[nH:35][cH:36][cH:37]3)[O:38]1.[Cl:1][c:2]1[n:3][c:4]([N:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([C:11]([CH3:12])([CH3:13])[OH:14])[cH:10]2>>[c:2]1(-[c:29]2[cH:30][c:31]3[c:32]([n:33][cH:34]2)[nH:35][cH:36][cH:37]3)[n:3][c:4]([N:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([C:11]([CH3:12])([CH3:13])[OH:14])[cH:10]2

Participants

3

Reactant 2

HCID 242087895-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridineHCID 866184422-(2-Chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)propan-2-ol

Product 1

HCID 595929832-(4-morpholino-2-(1H-pyrrolo[2,3-b]pyridin-5-yl)thieno[2,3-d]pyrimidin-6-yl)propan-2-ol

Sources & evidence

ORD record
ord-0e48f1ee37494ef2958cdd4a2f6b9723
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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