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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1906983Generated: October 26, 2026

Glyphosate → N-tert-Butylglycine

https://huagongshe.com/reaction/1906983

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlyphosateHCID 3496—
ReactantTert-ButylamineHCID 6385—
ReactantN-t-butyl-N-phosphonomethylglycineHCID 21917312—
ProductN-tert-ButylglycineHCID 414246—

Reaction Steps

Gaertner U.S. Pat. No. 3,927,080 describes the production of glyphosate by acid hydrolysis of N-t-butyl-N-phosphonomethylglycine or its esters. Tertiary butyl amine is reacted with a bromoacetate ester to produce an ester of N-t-butylglycine, which is in turn reacted with formaldehyde and phosphorous acid to produce the N-t-butyl-N-phosphonomethylglycine precursor.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04654429
Source datasetuspto-grants-1987_03
ORD IDord-2b7043972e844c9fa0812153b2358683
Source noteuspto-grants-1987_03