HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Alanine → benzyl (2S)-2-aminopropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Alanine | HCID 5950 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Lithium Bromide | HCID 82050 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | benzyl (2S)-2-aminopropanoate | HCID 726858 | — |
Reaction Steps
In a similar operation, 0.45 gram (0.005 mole) of alanine, 0.87 gram (0.01 mole) of lithium bromide, 0.95 gram (0.0055 mole) of benzyl bromide and 4.8 grams of N-methylpyrrolidinone were stirred together for 5.5 hours at 55° C. to obtain the desired benzyl alaninate product. High pressure liquid chromatographic assay showed yield of the product to be 89 percent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04654433 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-cfc221d72d9d44a29cddca406400fd4b |
| Source note | uspto-grants-1987_03 |