HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Cbz-2-amino 1-[di-(t-butyl)methoxy]propane → 2-Amino 1-[di-(t-butyl)methoxy]propane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Cbz-2-amino 1-[di-(t-butyl)methoxy]propane | HCID 20201216 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Amino 1-[di-(t-butyl)methoxy]propane | HCID 13907246 | — |
Reaction Steps
N-Cbz-2-Amino 1-[di-(t-butyl)methoxy]propane is dissolved in CH3OH and hydrogenated over 5% Pd/C in a Paar hydrogenation apparatus. When the reaction is complete the mixture is filtered through Celite and concentrated to yield 2-amino 1-[di-(t-butyl)methoxy]propane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04654439 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-88823774ccbf434181825942a9da696c |
| Source note | uspto-grants-1987_03 |