HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178436954, compound → 6-Ethylpyrimidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178436954 | HCID 178436954 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-Ethylpyrimidin-4-ol | HCID 135407688 | — |
Reaction Steps
90 g (0.58 mol) 4-Hydroxy-2-mercapto-6-ethylpyrimidine and 270 g Raney-Nickel are suspended in water (1000 mL) and the suspension is heated and stirred under reflux over night. The reaction mixture is filtered over celite and the filtrate is concentrated under reduced pressure to give crude product. Yield: 70.0 g (98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598157B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-1c5eeecf0c4e4681924a252e0cf90bd1 |
| Source note | uspto-grants-2013_12 |