HCID 178492059, compound → HCID 178492058, compound

HRID 1907229Notes

Reaction equation

HRID 1907229 reaction equation
NC1C=CC2NC=C3C(=O)N(C4C=CC=CC=4)N=C3C=2C=1.[CH3:22][O:23][C:24]1[CH:29]=[CH:28][C:27]([N:30]2[C:45](=[O:46])[C:33]3=[CH:34][NH:35][C:36]4[CH:37]=[CH:38][C:39]([N+:42]([O-])=O)=[CH:40][C:41]=4[C:32]3=[N:31]2)=[CH:26][CH:25]=1>>[NH2:42][C:39]1[CH:38]=[CH:37][C:36]2[NH:35][CH:34]=[C:33]3[C:45](=[O:46])[N:30]([C:27]4[CH:26]=[CH:25][C:24]([O:23][CH3:22])=[CH:29][CH:28]=4)[N:31]=[C:32]3[C:41]=2[CH:40]=1

Participants

3

Reactant 2

HCID 178492059HCID 178492059, compoundHCID 178507347HCID 178507347, compound

Product 1

HCID 178492058HCID 178492058, compound

Procedure

The title compound was prepared following the procedure for 6a using 5c. 1H-NMR (DMSO-d6) δ (ppm): 3.77 (3H, s), 6.75 (1H, dd, J=8.91, 2.37 Hz), 6.90 (2H, m), 7.10 (1H, d, J=2.08 Hz), 7.44 (1H, d, J=8.91 Hz), 8.05 (2H, m), 8.39 (1H, d, J=6.53 Hz). m/z 307.3 (MH+).

Sources & evidence

ORD record
ord-22bb78f2ce47487ab7fb5349d73d48ee
Source dataset
uspto-grants-2013_12
Patent number
US08598159B2

Reaction notes

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