(Bromomethyl)cyclobutane → HCID 66779432, compound

Participants

Reaction Steps

The title compound was prepared by the method of Preparation 54b using (R)-1-(4-fluorophenyl)-6-(6-methoxy pyridine-3-sulfonyl]-1,4,5,6,7,8-hexahydro-1,2,6-triaza-cyclopenta[b]naphthalene-4a-carboxylic acid and cyclobutylmethyl bromide. 1H NMR (400 MHz, CHCl3-d): δ 8.59 (d, 1H), 7.89 (dd, 1H), 7.45-7.37 (m, 3H), 7.16 (t, 2H), 6.84 (d, 1H), 6.42 (d, 1H), 4.40 (dd, 1H), 4.06 (dd, 2H), 4.01 (s, 3H), 3.89-3.81 (m, 1H), 3.28 (d, 1H), 2.88-2.81 (m, 1H), 2.58-2.51 (m, 4H), 2.03-1.92 (m, 2H), 1.79-1.70 (m, 4H).

Provenance & Evidence