6-bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine → HCID 46865564, compound

Participants

Reaction Steps

The title compound was prepared from (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)-1,3-oxazinan-2-one and 6-bromo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine following a procedure analogous to that described in Example 3. LC-MS Method 2 tR=1.27 min, 507, 485; 1H NMR (CD3OD) δ 0.97 (s, 3H), 1.29 (s, 3H), 1.58 (d, 3H), 2.18 (s, 2H), 2.27 (m, 1H), 2.51 (m, 2H), 2.63 (s, 3H), 3.10 (m, 1H), 5.62 (q, 1H), 7.13 (d, 2H), 7.30-7.40 (5H), 7.52 (d, 2H), 7.82 (d, 1H), 8.05 (d, 1H), 8.96 (s, 1H).

Provenance & Evidence