HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)piperazine → 1-[(6-Fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(4-fluorophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)piperazine | HCID 75260 | — |
| Reactant | Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate | HCID 66917965 | — |
| Product | 1-[(6-Fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(4-fluorophenyl)piperazine | HCID 11618222 | 85% |
Reaction Steps
Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(4-fluorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound (yield, 85%). 1H NMR (300 MHz, CDCl3): δ 3.19 (s, 4H), 3.77 (s, 3H), 4.13 (s, 4H), 6.88-7.02 (m, 4H), 7.23-7.27 (m, 1H), 7.45-7.71 (m, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-c51186c395a540c2ae5c0ecdf7947054 |
| Source note | uspto-grants-2013_12 |