HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chlorophenyl)piperazine → 1-[(6-Fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chlorophenyl)piperazine | HCID 1355 | — |
| Reactant | Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate | HCID 66917965 | — |
| Product | 1-[(6-Fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine | HCID 11596830 | 70% |
Reaction Steps
Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3-chlorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound (yield, 70%). 1H NMR (200 MHz, CDCl3): δ 3.30 (s, 4H), 3.76 (s, 3H), 4.13 (s, 4H), 6.77-6.91 (m, 3H), 7.15-7.33 (m, 3H), 7.44-7.58 (d, J=10.0 Hz, 1H), 7.58-7.75 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-615154c959a54b749f5ed84ad9538a72 |
| Source note | uspto-grants-2013_12 |