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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1907462Generated: November 1, 2026

1-(2-Pyrimidinyl)piperazine → HCID 66918244, compound

https://huagongshe.com/reaction/1907462

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
ReactantEthyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamateHCID 66917965—
ProductHCID 66918244HCID 6691824471%

Reaction Steps

Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(2-pyrimidyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound (yield, 71%). 1H NMR (200 MHz, CDCl3): δ 3.68 (s, 4H), 3.96 (s, 3H), 4.12 (s, 4H), 6.23 (t, J=4.4 Hz, 1H), 7.02 (s, 1H), 6.89-7.00 (m, 1H), 7.36-7.43 (m, 1H), 7.67 (m, 1H), 8.32 (d, J=4.4 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598173B2
Source datasetuspto-grants-2013_12
ORD IDord-60fdd9d229b443638acab58c5a4de765
Source noteuspto-grants-2013_12