HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Pyrimidinyl)piperazine → HCID 66918244, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Pyrimidinyl)piperazine | HCID 88747 | — |
| Reactant | Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate | HCID 66917965 | — |
| Product | HCID 66918244 | HCID 66918244 | 71% |
Reaction Steps
Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(2-pyrimidyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound (yield, 71%). 1H NMR (200 MHz, CDCl3): δ 3.68 (s, 4H), 3.96 (s, 3H), 4.12 (s, 4H), 6.23 (t, J=4.4 Hz, 1H), 7.02 (s, 1H), 6.89-7.00 (m, 1H), 7.36-7.43 (m, 1H), 7.67 (m, 1H), 8.32 (d, J=4.4 Hz, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-60fdd9d229b443638acab58c5a4de765 |
| Source note | uspto-grants-2013_12 |