HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Chlorophenyl)piperazine → 1-[(2-Methoxy-6-methylquinoxalin-3-yl)aminocarbonyl]-4-(2-chlorophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Chlorophenyl)piperazine | HCID 415628 | — |
| Reactant | Ethyl N-(2-methoxy-6-methylquinoxalin-3-yl)carbamate | HCID 66917958 | — |
| Product | 1-[(2-Methoxy-6-methylquinoxalin-3-yl)aminocarbonyl]-4-(2-chlorophenyl)piperazine | HCID 66918201 | 66% |
Reaction Steps
Ethyl N-(2-methoxy-6-methylquinoxalin-3-yl)carbamate and 1-(2-chlorophenyl)piperazine were reacted by the same way with the example 43 to obtain the titled compound (yield, 66%). 1H NMR (300 MHz, CDCl3): δ 2.43-2.49 (m, 3H), 3.10-3.15 (m, 4H), 3.81 (s, 3H), 3.08-4.12 (m, 4H), 7.00-7.12 (m, 3H), 7.24-7.40 (m, 3H), 7.49-7.65 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-aa257d178dbe4f61aed7e364fa746cb2 |
| Source note | uspto-grants-2013_12 |