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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1907528Generated: November 1, 2026

1-(2-Pyrimidinyl)piperazine → HCID 66918066, compound

https://huagongshe.com/reaction/1907528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
ReactantEthyl N-(2,6-dimethoxyquinoxalin-3-yl)carbamateHCID 66918080—
ProductHCID 66918066HCID 6691806680%

Reaction Steps

Ethyl N-(2,6-dimethoxyquinoxalin-3-yl)carbamate and 1-(2-pyrimidyl)piperazine were reacted by the same way with the example 64 to obtain the titled compound (yield, 80%). 1H NMR (300 MHz, CDCl3): δ 3.72 (s, 3H), 3.87-3.96 (m, 7H), 4.12-4.15 (m, 4H), 6.54 (t, J=4.8 Hz, 1H), 6.92 (s, 1H), 7.04-7.36 (m, 3H), 7.62 (m, 1H), 8.34 (d, J=4.8 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598173B2
Source datasetuspto-grants-2013_12
ORD IDord-f48af2285be04be4a315e191a92b620d
Source noteuspto-grants-2013_12