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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1907536Generated: October 26, 2026

1-(3,5-Dimethoxyphenyl)piperazine → 1-[(6-Fluoro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine

https://huagongshe.com/reaction/1907536

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,5-Dimethoxyphenyl)piperazineHCID 2736205—
Reactantethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamateHCID 69243333—
Product1-[(6-Fluoro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazineHCID 6924349576%

Reaction Steps

Ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate and 1-(3,5-dimethoxyphenyl)piperazine were reacted by the same way with the example 85 to obtain the titled compound (yield, 76%). MS(ESI) m/z 442 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598173B2
Source datasetuspto-grants-2013_12
ORD IDord-e191c39310494828b9a4705f9e2b680d
Source noteuspto-grants-2013_12