HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chlorophenyl)piperazine → 1-[(6-Fluoro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chlorophenyl)piperazine | HCID 1355 | — |
| Reactant | ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate | HCID 69243333 | — |
| Product | 1-[(6-Fluoro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine | HCID 69243107 | 82% |
Reaction Steps
Ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate and 1-(3-chlorophenyl)piperazine were reacted by the same way with the example 85 to obtain the titled compound (yield, 82%). 1H NMR (200 MHz, CDCl3): δ 3.30 (s, 4H), 3.91 (s, 4H), 4.15 (s, 3H), 6.79-6.91 (m, 3H), 7.17-7.42 (m, 4H), 7.79 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-c20a8206ac4c4eed905e27e35f34f7db |
| Source note | uspto-grants-2013_12 |