HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Mepp → 1-[(6-Chloro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(2-methylphenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Mepp | HCID 91965 | — |
| Reactant | HCID 69241674 | HCID 69241674 | — |
| Product | 1-[(6-Chloro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(2-methylphenyl)piperazine | HCID 69243768 | 89% |
Reaction Steps
Ethyl N-(6-chloro-3-methoxyquinoxalin-2-yl)carbamate and 1-(2-methylphenyl)piperazine were reacted by the same way with the example 106 to obtain the titled compound (yield, 89%). H NMR (300 MHz, CDCl3): δ 2.35 (s, 3H), 3.01 (s, 4H), 3.76 (s, 4H), 4.14 (s, 3H), 7.03-7.52 (m, 6H), 7.68-7.77 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-0fdacc8c79aa47078e7fef4b14f87e8c |
| Source note | uspto-grants-2013_12 |