HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methoxyphenyl)piperazine → 1-[(3-Methoxy-6-methylquinoxalin-2-yl)aminocarbonyl]-4-(2-methoxyphenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| Reactant | ethyl N-(3-methoxy-6-methylquinoxalin-2-yl)carbamate | HCID 69243736 | — |
| Product | 1-[(3-Methoxy-6-methylquinoxalin-2-yl)aminocarbonyl]-4-(2-methoxyphenyl)piperazine | HCID 69240660 | 90% |
Reaction Steps
Ethyl N-(3-methoxy-6-methylquinoxalin-2-yl)carbamate and 1-(2-methoxyphenyl)piperazine were reacted by the same way with the example 127 to obtain the titled compound (yield, 90%). 1H NMR (300 MHz, CDCl3): δ 2.49 (s, 3H), 3.09-3.18 (m, 4H), 3.77-3.82 (m, 4H), 3.88 (s, 3H), 4.13 (s, 3H), 6.87-7.80 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-7fd081efbefe45879fc7500f994a690d |
| Source note | uspto-grants-2013_12 |