HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chlorophenyl)piperazine → 1-[(3-Methoxy-6-methylquinoxalin-2-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chlorophenyl)piperazine | HCID 1355 | — |
| Reactant | ethyl N-(3-methoxy-6-methylquinoxalin-2-yl)carbamate | HCID 69243736 | — |
| Product | 1-[(3-Methoxy-6-methylquinoxalin-2-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine | HCID 69244308 | 87% |
Reaction Steps
Ethyl N-(3-methoxy-6-methylquinoxalin-2-yl)carbamate and 1-(3-chlorophenyl)piperazine were reacted by the same way with the example 127 to obtain the titled compound (yield, 87%). 1H NMR (300 MHz, CDCl3): δ 2.46 (s, 3H), 3.19-3.33 (m, 4H), 3.72-3.77 (m, 4H), 4.13 (s, 3H), 6.79-7.66 (m, 7H), 7.71 (d, J=8.6 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-5bf20a6178944471b762b6941aedfae7 |
| Source note | uspto-grants-2013_12 |