HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(m-Tolyl)piperazine → 1-[(3,6-Dimethoxyquinoxalin-2-yl)aminocarbonyl]-4-(3-methylphenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(m-Tolyl)piperazine | HCID 83111 | — |
| Reactant | ethyl N-(3,6-dimethoxyquinoxalin-2-yl)carbamate | HCID 69244324 | — |
| Product | 1-[(3,6-Dimethoxyquinoxalin-2-yl)aminocarbonyl]-4-(3-methylphenyl)piperazine | HCID 69241696 | 86% |
Reaction Steps
Ethyl N-(3,6-dimethoxyquinoxalin-2-yl)carbamate and 1-(3-methylphenyl)piperazine were reacted by the same way with the example 148 to obtain the titled compound (yield, 86%). 1H NMR (300 MHz, CDCl3): δ 2.33 (s, 3H), 3.26-3.29 (m, 4H), 3.73-3.77 (m, 4H), 3.90 (s, 3H), 4.13 (s, 3H), 6.73-6.77 (m, 3H), 7.13-7.22 (m, 4H), 7.74 (d, J=9.8 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-b33317bdcd654fabbf7249c0d33bbe34 |
| Source note | uspto-grants-2013_12 |