Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3,5-Dimethoxyphenyl)piperazine → 1-[(6,7-Difluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3,5-Dimethoxyphenyl)piperazine | HCID 2736205 | — |
| 반응물 | Ethyl N-(6,7-difluoro-2-methoxyquinoxalin-3-yl)carbamate | HCID 69244192 | — |
| 생성물 | 1-[(6,7-Difluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine | HCID 69240969 | 70% |
반응 단계
Ethyl N-(6,7-difluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3,5-dimethoxyphenyl)piperazine were reacted by the same way with the example 169 to obtain the titled compound (yield, 70%). MS (ESI) m/z 460 ([M+H]+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08598173B2 |
| 출처 데이터셋 | uspto-grants-2013_12 |
| ORD ID | ord-f77c301f105b4daca8e884174415bea0 |
| 출처 메모 | uspto-grants-2013_12 |