Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3,5-Dimethylphenyl)piperazine → 1-[(6,7-Dichloro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3,5-Dimethylphenyl)piperazine | HCID 2758626 | — |
| 반응물 | Ethyl N-(6,7-dichloro-2-methoxyquinoxalin-3-yl)carbamate | HCID 69243293 | — |
| 생성물 | 1-[(6,7-Dichloro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine | HCID 69243271 | 55% |
반응 단계
Ethyl N-(6,7-dichloro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3,5-dimethylphenyl)piperazine were reacted by the same way with the example 176 to obtain the titled compound (yield, 55%). 1H NMR (300 MHz, CDCl3) δ 2.30 (s, 6H), 3.16-3.21 (m, 4H), 3.75-3.79 (m, 4H), 4.15 (s, 3H), 6.52-6.59 (m, 3H), 7.31 (br s, 1H), 7.85 (s, 1H), 7.92 (s, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08598173B2 |
| 출처 데이터셋 | uspto-grants-2013_12 |
| ORD ID | ord-65d0596014b84ca98c7f3a10289c0085 |
| 출처 메모 | uspto-grants-2013_12 |