1-(3-Bromophenyl)piperazine → 1-[(2-Methoxy-6,7-dimethylquinoxalin-3-yl)aminocarbonyl]-4-(3-bromophenyl)piperazine

Participants

Reaction Steps

Ethyl N-(2-methoxy-6,7-dimethylquinoxalin-3-yl)carbamate and 1-(3-bromophenyl)piperazine were reacted by the same way with the example 183 to obtain the titled compound (yield, 69%). 1H NMR (300 MHz, CDCl3) δ 2.33 (s, 3H), 2.40 (s, 3H), 3.22-3.31 (m, 4H), 3.73-3.76 (m, 3H), 4.13 (s, 4H), 6.85 (m, 1H), 7.00-7.20 (m, 3H), 7.40 (br s, 1H), 7.53 (s, 1H), 7.59 (s, 1H).

Provenance & Evidence