HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,5-Dimethylphenyl)piperazine → 1-[(2,6,7-Trimethoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,5-Dimethylphenyl)piperazine | HCID 2758626 | — |
| Reactant | Ethyl N-(2,6,7-trimethoxyquinoxalin-3-yl)carbamate | HCID 69244380 | — |
| Product | 1-[(2,6,7-Trimethoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine | HCID 69244840 | 56% |
Reaction Steps
Ethyl N-(2,6,7-trimethoxyquinoxalin-3-yl)carbamate and 1-(3,5-dimethylphenyl)piperazine were reacted by the same way with the example 190 to obtain the titled compound (yield, 56%). 1H NMR (300 MHz, CDCl3) δ 2.28 (s, 3H), 2.30 (s, 3H), 3.26 (m, 4H), 3.77 (m, 4H), 3.97 (s, 3H), 4.00 (s, 3H), 4.13 (s, 3H), 6.59 (s, 3H), 7.14 (s, 1H), 7.27 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-172ca9a17ee14e9ab1e048b56431723f |
| Source note | uspto-grants-2013_12 |