HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chlorophenyl)piperazine → 1-[(2,6,7-Trimethoxyquinoxalin-3-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chlorophenyl)piperazine | HCID 1355 | — |
| Reactant | Ethyl N-(2,6,7-trimethoxyquinoxalin-3-yl)carbamate | HCID 69244380 | — |
| Product | 1-[(2,6,7-Trimethoxyquinoxalin-3-yl)aminocarbonyl]-4-(3-chlorophenyl)piperazine | HCID 69240824 | 74% |
Reaction Steps
Ethyl N-(2,6,7-trimethoxyquinoxalin-3-yl)carbamate and 1-(3-chlorophenyl)piperazine were reacted by the same way with the example 190 to obtain the titled compound (yield, 74%) H NMR (300 MHz, CDCl3) δ 3.29-3.31 (m, 4H), 3.79 (m, 4H), 3.97 (s, 3H), 4.00 (s, 3H), 4.12 (s, 3H), 6.82 (m, 1H), 6.86-6.88 (m, 1H), 6.89-6.91 (m, 1H), 7.14 (s, 1H), 7.19-7.22 (m, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-6d879622f4534de6bdce3342e9a41941 |
| Source note | uspto-grants-2013_12 |