Hydrogen Peroxide → HCID 68526433, compound

Participants

Reaction Steps

To a suspension of 17 g (0.084 mol) of 1,2-Dimethyl-1H-[4,4]bipyrimidinyl-6-one in 45 mL of water, were added 8.5 mL of sulfuric acid, 25 mL of carbon tetrachloride and 9.6 g (0.037 mol) of iodide. The resulting mixture was refluxed and 16.38 mL of hydrogen peroxide (35% solution in water) was added dropwise. The mixture was stirred under reflux for 5 h and cooled at room temperature, 100 mL of saturated aqueous solution of ammonium chloride and 100 mL of chloroform were added. The resulting precipitate was filtered off, the filtrate extracted with chloroform, dried and evaporated to afford 13.6 g of product witch was used as such in the next step.

Provenance & Evidence