HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 59737588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | tert-Butyl (2-amino-4-(thiophen-2-yl)phenyl)carbamate | HCID 57717474 | — |
| Reactant | HCID 59737551 | HCID 59737551 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59737588 | HCID 59737588 | 68% |
Reaction Steps
Following the same procedure as described in Example 1a, step 6 (scheme 1) and using compound 4 but substituting compound 7 for compound 99, the title compound 100 was obtained (0.407 g, 68% yield) [after flash chromatography (eluent: 10% isopropanol in DCM with 0.1% triethylamine)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598168B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-790b786a04d84d79a178daa2a0eda360 |
| Source note | uspto-grants-2013_12 |