HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(2-hydroxyethyl)amino]-3-nitrobenzoic acid → HCID 4043952, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(2-hydroxyethyl)amino]-3-nitrobenzoic acid | HCID 2909623 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | HCID 4043952 | HCID 4043952 | 101.9% |
Reaction Steps
A solution of intermediate 156 (1.33 g, 5.9 mmol) in AcOEt/MeOH was stirred under H2 in the presence of 10% palladium on carbon for 18 h, filtered through Celite®, concentrated and then triturated with DCM to give compound 157 (1.18 g, >99% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598168B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-591ae15508a246328e5d51b509857afc |
| Source note | uspto-grants-2013_12 |