Hydrochloric Acid → HCID 59737566, compound

Participants

Reaction Steps

LiOH.H2O (1.14 g, 27.26 mmol) and water (5 mL) was added to a solution of 324 (4.36 g, 13.62 mmol) in THF (15 mL) and MeOH (15 mL). The reaction mixture was stirred at room temperature for 22 h, diluted with water and acidified with HCl (pH 4-5). The precipitate obtained was collected by filtration and rinsed with water to give the title compound 325 (3.91 g, 94% yield) as a white solid.

Provenance & Evidence