反应详情

To a stirred solution of 393 (1.2 g, 4.26 mmol) in MeOH (20 mL) was added palladium on charcoal (250 mg). The flask was purged with hydrogen gas for 1 minute and then the reaction was stirred under a hydrogen atmosphere for 15 hours. The palladium was filtered off through Celite and the filtrate was evaporated via rotary evaporation, and the resulting solid dried under vacuum to afford 394 as a white solid (700 mg, 86%).

1. customThe flask was purged with hydrogen gas for 1 minute
2. filtrationThe palladium was filtered off through Celite
3. customthe filtrate was evaporated via rotary evaporation
4. customthe resulting solid dried under vacuum