HCID 59737356, compound → HCID 59737289, compound

Participants

Reaction Steps

A solution of 443 (0.13 g, 0.206 mmol) in TFA (0.392 mL) and water (0.021 mL) was stirred for 2 h at room temperature. The solvent was evaporated and the residue obtained was dissolved in EtOAc, washed with sat NaHCO3 and sat NaCl. The organic layer was dried with MgSO4, filtered and concentrated to a brown solid. Trituration in Et2O generated the title compound 444 as a beige powder (70 mg, 82% yield).

Provenance & Evidence