Methanol → Benzoic acid, 4-[2-(methoxycarbonyl)phenoxy]-3-nitro-, methyl ester

Participants

Reaction Conditions

Reaction Steps

Concentrated H2SO4 (3 mL) was added to a solution of compound 545 (7.5 g, 23.64 mmol) in MeOH (80 mL) and stirred at 60° C. for 16 h. MeOH was removed under vacuum and the crude product was dissolved in AcOEt and washed with water. The organic layer was separated, dried with Na2SO4, filtered and concentrated via rotary evaporation to afford the title compound 546 (6.2 g, 79%) as a light yellow solid.

Provenance & Evidence