Methanol → Methyl 4-aminopyridine-2-carboxylate

HRID 1907883Notes

Reaction equation

HRID 1907883 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([OH:10])=[O:9])[CH:3]=1.S(=O)(=O)(O)O.[CH3:16]O>>[CH3:16][O:9][C:8](=[O:10])[C:4]1[CH:3]=[C:2]([NH2:1])[CH:7]=[CH:6][N:5]=1

Participants

4

Reactant 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 20501324-Aminopicolinic acid

Product 1

HCID 3759117Methyl 4-aminopyridine-2-carboxylate

Procedure

Prepared analogously to example 366a from 4-aminopicolinic acid and sulfuric acid in methanol.

Sources & evidence

ORD record
ord-85f3cf33c1fd4970a278355b165a6273
Source dataset
uspto-grants-2013_12
Patent number
US08598190B2

Reaction notes

Loading…