HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → HCID 66958505, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | tert-Butyl 2-(3-aminoquinolin-4-ylamino)ethylcarbamate | HCID 12016824 | — |
| Product | HCID 66958505 | HCID 66958505 | 72% |
Reaction Steps
Using the general method of Examples 43-68 Part A, tert-butyl[2-(3-aminoquinolin-4-ylamino)ethyl]carbamate (43.5 g, 144 mmol) was reacted with chloroacetyl chloride (17.72 g, 158 mmol) to provide 37.39 g of tert-butyl[2-(2-chloromethyl-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]carbamate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598192B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-1313bd1ca4f54388bf9bdf3efccb6208 |
| Source note | uspto-grants-2013_12 |