HRID190817

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID923

Sodium ion

Na+

HCID166653

Hydride

H-

HCID608487

6-Trifluoromethyloxindole

C9H6F3NO

HCID11823941

4-chloro-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazoline

C16H20ClN3O3

PRODUCTS

生成物

结构：COc1cc2c(C3C(=O)Nc4cc(C(F)(F)F)ccc43)ncnc2cc1OCCCN1CCOCC1

HCID21717294

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2c3e224c86b24169b1c343f301fc9d0d
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反应 SMILES

[Cl:17][c:18]1[n:19][cH:20][n:21][c:22]2[cH:23][c:24]([O:30][CH2:31][CH2:32][CH2:33][N:34]3[CH2:35][CH2:36][O:37][CH2:38][CH2:39]3)[c:25]([O:28][CH3:29])[cH:26][c:27]12.[F:3][C:4]([c:5]1[cH:6][cH:7][c:8]2[c:12]([cH:13]1)[NH:11][C:10](=[O:14])[CH2:9]2)([F:15])[F:16].[H-:1].[Na+:2]>>[F:3][C:4]([c:5]1[cH:6][cH:7][c:8]2[c:12]([cH:13]1)[NH:11][C:10](=[O:14])[CH:9]2[c:18]1[n:19][cH:20][n:21][c:22]2[cH:23][c:24]([O:30][CH2:31][CH2:32][CH2:33][N:34]3[CH2:35][CH2:36][O:37][CH2:38][CH2:39]3)[c:25]([O:28][CH3:29])[cH:26][c:27]12)([F:15])[F:16]