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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1908263Generated: October 27, 2026

2-Pyridinemethanamine → 2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)-N-(3-hydroxy-4-oxo-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl)nicotinamide

https://huagongshe.com/reaction/1908263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridinemethanamineHCID 19509—
Reactant3-(2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)nicotinamido)-2-hydroxy-4-phenylbutanoic acidHCID 67239352—
Product2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)-N-(3-hydroxy-4-oxo-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl)nicotinamideHCID 67237840—

Reaction Steps

The reaction was carried out in analogy to reaction step 1.3 by reacting 3-(2-(3-(4-fluorophenyl)-1H-pyrazol-1-yl)nicotinamido)-2-hydroxy-4-phenylbutanoic acid with pyridin-2-ylmethylamine; ESI-MS [M+H]+: 551.5

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598211B2
Source datasetuspto-grants-2013_12
ORD IDord-0a3260dbc39d42f6bfdc2703f4e20bc7
Source noteuspto-grants-2013_12