HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanemethanamine → N-(4-(Cyclopropylmethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | 2-hydroxy-4-phenyl-3-(2-(3-phenyl-1H-pyrazol-1-yl)nicotinamido)butanoic acid | HCID 67238194 | — |
| Product | N-(4-(Cyclopropylmethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide | HCID 67238090 | — |
Reaction Steps
The reaction was carried out in analogy to reaction step 1.3 by reacting 2-hydroxy-4-phenyl-3-(2-(3-phenyl-1H-pyrazol-1-yl)nicotinamido)butanoic acid with cyclopropylmethylamine; ESI-MS [M+H]+: 496.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598211B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-cb5c05bd6cc3459d9178f877643c65af |
| Source note | uspto-grants-2013_12 |