HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-ethyl-6-nitro-2,3-dihydro-1H-indole → 5-ethyl-6-nitro-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-ethyl-6-nitro-2,3-dihydro-1H-indole | HCID 57470205 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-ethyl-6-nitro-1H-indole | HCID 57470206 | 100.9% |
Reaction Steps
To a solution of 5-ethyl-6-nitroindoline (1.9 g, 9.9 mmol) in CH2Cl2 (30 mL) was added MnO2 (4.0 g, 46 mmol). The mixture was stirred at ambient temperature for 8 h. The solid was filtered off and the filtrate was concentrated to dryness to give 5-ethyl-6-nitro-1H-indole (1.9 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598181B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-8a8ee449e34a42169f37d667b6f133c2 |
| Source note | uspto-grants-2013_12 |