HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylethylamine → 2-Ethyl-6-(ethyl-methyl-amino)-isonicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylethylamine | HCID 12219 | — |
| Reactant | 2-Dimethylamino-6-ethyl-isonicotinic acid | HCID 58418101 | — |
| Product | 2-Ethyl-6-(ethyl-methyl-amino)-isonicotinic acid | HCID 58418016 | — |
Reaction Steps
2-Ethyl-6-(ethyl-methyl-amino)-isonicotinic acid is prepared in analogy to 2-dimethylamino-6-ethyl-isonicotinic acid using ethyl-methyl-amine; LC-MS: tR=0.56 min; [M+1]+=209.20; 1H NMR (D6-DMSO: δ 1.16 (t, J=7.0 Hz, 3H), 1.24 (t, J=7.3 Hz, 3H), 2.95 (q, J=7.0 Hz, 2H), 3.57 (s, 3H), 3.76 (q, J=6.3 Hz), 6.98 (s, 1H), 7.23 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598208B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-e50d612979164e689cc2b07339d3c33c |
| Source note | uspto-grants-2013_12 |