N-Methylisopropylamine → HCID 58418063, compound

HRID 1908795Notes

Reaction equation

[CH2:1]([N:3]([CH2:15][CH3:16])[C:4]1[C:12]([CH2:13][CH3:14])=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][N:5]=1)C.[CH:17](NC)(C)C>>[CH2:13]([C:12]1[C:4]([N:3]([CH:15]([CH3:16])[CH3:17])[CH3:1])=[N:5][CH:6]=[C:7]([CH:11]=1)[C:8]([OH:10])=[O:9])[CH3:14]

Participants

Reactant 2

HCID 78485N-Methylisopropylamine

HCID 58418086HCID 58418086, compound

Product 1

HCID 58418063HCID 58418063, compound

Procedure

The title compound is prepared in analogy to 6-diethylamino-5-ethyl-nicotinic acid using isopropyl-methylamine; LC-MS: tR=0.64 min, [M+1]+=223.14.

Sources & evidence

ORD record: ord-5c7b32244a064e828c146465bbfd5cfb
Source dataset: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08598208B2

Reaction notes

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